Funtions and Side Effects of Soy Isoflavones

Soy isoflavones and their metabolites also have biological activities that are unrelated to their interactions with estrogen receptors . By inhibiting the synthesis and activity of certain enzymes involved in estrogen metabolism, soy isoflavones may alter the biological activity of endogenous estrogens and androgens . Soy isoflavones have also been found to inhibit tyrosine kinases , enzymes that play critical roles in the signaling pathways that stimulate cell proliferation.

Estrogen Function

Soybean isoflavones are representative plant estrogen. It can replace estrogen and combine with ER to exert estrogen function. The estrogen function of soybean isoflavones have defending and treating effect to blood fat hoist, atherosclerosis and osteoporosis which are arosed by old lady's hormone retreat.
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Breast Cancer

A U.S.-Chinese research team conducted a large-scale study to determine what, if any, effect the consumption of soy-based foods would have on the risk of recurrence among breast cancer survivors. Researchers assembled a study group of more than 9,500 U.S. and Chinese women who had survived invasive breast cancer. The research team monitored and measured the women’s intake of soy isoflavones over the course of more than seven years. At the end of the study period, they found that soy isoflavone intake significantly reduced the risk of breast cancer recurrence and also slightly lowered the risk of breast cancer mortality, but at a rate considered statistically insignificant. Researchers published their findings in the July 2012 issue of “The American Journal of Clinical Nutrition.”
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Side effects and safety of soy isoflavones

Consuming soy foods such as soy protein is LIKELY SAFE. Taking soy dietary supplements also seems to be safe for most people when used short-term (up to six months). Soy can cause some mild...